Minimally invasive biopsy-based diagnostics in support of precision cancer medicine
Bo Franzén, Gert Auer, Rolf Lewensohn
A review published in Mol. Oncol. 2024
FNA as a Patient-Friendly Method
FNA is described as less traumatic and potentially more accurate than core needle biopsies, making it a more patient-friendly approach for tumor sampling.
Molecular Analysis of FNA
The review emphasizes the feasibility and growing importance of using ultrasensitive molecular methods on FNA samples to analyze mutations, RNA transcripts, and proteins within the tumor microenvironment.
Support for Precision Medicine
Combining FNA with molecular diagnostics can provide continuous tumor information to support treatment decisions, improve patient outcomes, and facilitate drug development
Potential for Repeated Sampling
Due to its minimally invasive nature and improved molecular analysis techniques, FNA is well-suited for facilitating repeated biopsies during different treatment phases to track resistance and inform clinical management.
